ProBactilardii®

product code: DLCFPBAC010200

Your price 54,90 €

+ -

ProBactilardii^® is a food supplement consisting of 2 complementary capsules. The Synbiotic capsule contains a prebiotic (in the form of acacia fibre) and the proprietary BACTILARDII^® probiotic formula, based on 4 bacterial strains and 1 yeast strain, whose viability is guaranteed at the end of the product's shelf life. The Postbiotic capsule contains a postbiotic in a formula based on butyric acid. ProBactilardii^®features not only an innovative composition, but also a patented formula and direct packaging, ensuring maximum protection of microbial strains contained inside the capsule.

ProBactilardii^® is a food supplement consisting of 2 complementary capsules. The Synbiotic capsule contains a prebiotic (in the form of acacia fibre) and the proprietary BACTILARDII^® probiotic formula, based on 4 bacterial strains and 1 yeast strain, whose viability is guaranteed at the end of the product's shelf life. The Postbiotic capsule contains a postbiotic in a formula based on butyric acid. ProBactilardii^®features not only an innovative composition, but also a patented formula and direct packaging, ensuring maximum protection of microbial strains contained inside the capsule.

What lives inside us?

The gut microbiota of a healthy human consists of approximately 100 trillion (!) beneficial microorganisms (bacteria, fungi and even viruses), which exceeds the total number of cells in the human body tenfold.

Up to 500-1000 beneficial species of microorganisms can live in the human intestines, most in the large intestine. The composition of the microbiota depends on many factors, however bacteria of the genus Bacteroides, Bifidobacterium and Lactobacillus are almost always dominant.

In addition to genetic determinants, the composition of gut microbiota can be affected mainly by age, diet, geographical region, sanitation and medicines used.

The composition and population of the microbiome can be affected by, among other things:

excessive stress,

change in lifestyle,

fatigue,

diseases,

antibiotic use,

sudden change in diet, e.g. due to a change in location, travel to tropical or exotic countries with a different diet.

Microorganisms naturally present in the human body have many useful functions, including beneficial effects on:

What makes ProBactilardii^® so special?

Innovative composition

Proprietary Bactilardii^® formula

Concentrated formula

Viability

Stability and viability of microorganisms

Resistance during passage through the gastrointestinal tract

Ideal proportions

Recyclable packaging (You can find more information on recycling in the "Storage" tab)

Optimal protection of strains

Convenience

Ingredients of natural origin only

Less is more

Vegan

Innovative composition – a combination of prebiotic, probiotic and postbiotic in one product

PROBIOTICS are products containing selected live strains of microorganisms support the human body by maintaining the balance of the gut microbiota. The strains contained in ProBactilardii^® have broad, clinically documented health-promoting properties.

PREBIOTICS are products that are used by the beneficial microorganisms of the human microflora (mainly the intestinal microflora, but not exclusively), supporting the optimal function of the human body. The acacia fibre used in ProBactilardii^® is a soluble fibre type.

POSTBIOTICS are defined as the combination of all bioactive ingredients produced by bacteria, for example during fermentation, that support the human body. Another ingredient used in ProBactilardia^® is butyric acid. It is naturally biosynthesized in the large intestine and its supplementation can support the effects of butyric acid synthesized in the intestines.

Proprietary Bactilardii^® formula

4 strains of live, freeze-dried, selected and branded bacterial strains (Bifidobacterium bifidum Rosell^® R0071, Bifidobacterium longum Rosell^® R0175, Lactobacillus helveticus Rosell^® R0052 and Lactobacillus rhamnosus Rosell^® R0011) in DUOLIFE proprietary proportions plus 1 billion yeast strains (Saccharomyces boulardii CNCM I-1079).

BACTILARDII^®is a formula created exclusively for DUOLIFE by a world expert in probiotics
– Canadian company Lallemand.

Concentrated formula

Concentrated formula - the total amount of microorganisms is 9 billion CFU = 9x10⁹ CFU (CFU = colony-forming unit) of LIVE freeze-dried bacteria and yeast cultures GUARANTEED in the formula AT THE END OF THE PRODUCT'S SHELF LIFE. Concentrated dose guarantees convenient use, usually once per day, both capsules together.

Concentrated dose guarantees convenient use, usually once per day, both capsules together.

The combined use involves taking 2 capsules at once – the synbiotic in the first capsule and the postbiotic in the second capsule.

Stability and viability of microorganisms

Laboratory-confirmed viability of bacterial and yeast cultures is guaranteed in the formula at the end of the product's shelf life. Stability and viability of microorganisms was tested and laboratory-confirmed in reputed laboratories in the United States and Canada.

Results of the conducted research show that the number of live bacteria cultures in ProBactilardii® is compliant with the amount stated on the product label during the entire storage period, up until the end of the best before date, while stored at room temperature (with no necessity to refrigerate the product).

Stability tests were also conducted in real time covering 24 months: from the production date until the finish of the best before date in conditions resembling storage conditions indicated on the product label.

The stability test was performed at the Lallemand Health Solutions laboratory in Canada, in line with the ICH Q1A (R2) international guidelines for pharmaceutical products. ICH guidelines are the main applicable criteria for stability testing of pharmaceutical products. They were developed by the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, ICH.

Adhesion to intestinal epithelial cells - do you know how probiotics work?

Figure 1: The barrier effect of Lacticaseibacillus rhamnosus Rosell^® R0011 (A) and Lactobacillus helveticus Rosell^® R0052 (B) strains and their adhesion to the intestinal epithelium conditioning probiotic activity was demonstrated.

Resistance during passage through the gastrointestinal tract

Resistance during passage through the gastrointestinal tract has been confirmed in an experimental study performed for the R0052 and R0011 strains using an in vitro model (IViDiS, in vitro Digestive System). It confirms the good stability of the strains in gastric and duodenal environment [1.]

Conclusions: The survival of the R0052 and R0011 strains is optimal up to 90 minutes of passage through the stomach and another 90 minutes through the duodenum, which allows to infer the stability of the strains throughout the passage through the upper part of the gastrointestinal tract under physiological conditions.

Clinical trials in healthy volunteers taking the food supplement with the R0011 strain showed good survival of bacteria throughout the human gastrointestinal tract [2].

Conclusions: The number of R0011 strain bacilli in the faeces of the subjects before consuming the supplement (3 weeks, exclusion) and during consumption (12 days, consumption) and during the one-week wash-out period.

Ideal proportions

The strains in this product have been used in DUOLIFE proprietary proportions and in the full portions used in many clinical trials.

Optimal protection of strains

Proprietary innovative formulation protects strains from adverse conditions and from stomach acid and bile with proprietary BIO-SUPPORT™ technology. The stability of the strains within the gastrointestinal tract has been proven in preclinical in vitro tests and in clinical trials. The microgranules are further protected by delayed-release HPMC capsules, all encapsulated in patented, drug-certified ACTIV-VIAL™ direct packaging with Activ-Polymer™ lining that minimizes the ingress of moisture, light and oxygen to the capsules in the container, protecting bacterial and yeast strains and other ingredients during product storage

BIO-SUPPORT™ technology action scheme – ensuring protection of all
Lallemand strains

Patented, innovative, drug-certified ACTIV-VIAL™ direct packaging

Convenience

It does not require refrigeration. Recommended storage at room temperature (20-25°C).

Ingredients of natural origin

Including 4 bacterial strains and 1 yeast strain in the form of LIVE freeze-dried microorganisms. The natural substance that protects the strains against the harmful effects of atmospheric oxygen is vitamin C of natural origin - L-ascorbic acid (described on the label as an antioxidant, pursuant to the EU Regulation (EC) 1333/2008).

Less is more

No artificial fillers, GMO- and gluten-free.

Vegan

Suitable for vegans and vegetarians

Things to pay particular attention to when choosing the best probiotic for you and your loved ones:

Does it contain live bacteria cultures?

What strains does the product contain?

What number of strains does it contain?

Are the strains selected and branded?

Have the strains been clinically tested?

Besides probiotics, does the product contain prebiotics and a postbiotic?

Does it contain live yeasts and in what amount?

What is the declared live culture content at the end of the product's shelf life?

Has the product been tested on stability?

Does the product need to be stored in the refrigerator?

Does the packaging protect against light, moisture and temperature?

Why is ProBactilardii^® the right product for you and your loved ones?

Besides probiotics, does the product contain prebiotics and a postbiotic?

Yes

Does it contain live yeasts and in what amount?

Yes, 2 x 10⁹ CFU (CFU =
colony-forming unit)

Does it contain live bacteria cultures?

Yes

What number of strains does it contain?

9 billion CFU = 9 x 10⁹ CFU
(CFU = colony-forming unit)

What is the declared live culture content at the end of the product's expiration date?

9 billion CFU = 9 x 10⁹ CFU (CFU = colony-forming unit)

Have the strains been clinically tested?

Yes

Does the packaging protect against light and moisture from the air?

Yes

Does the product need to be stored in the refrigerator?

ProBactilardii^®

See frequently asked questions.

Go to FAQ→

References

[1] Tompkins, T., Mainville, I., & Arcand, Y. (2011). The impact of meals on a probiotic during transit through a model of the human upper gastrointestinal tract. Beneficial microbes, 2(4), 295-303.

[2] Firmesse, O., Mogenet, A., Bresson, J. L., Corthier, G., & Furet, J. P. (2008). Lactobacillus rhamnosus R11 consumed in a food supplement survived human digestive transit without modifying microbiota equilibrium as assessed by real-time polymerase chain reaction. Journal of molecular microbiology and biotechnology, 14(1-3), 90-99.

Ingredients: Synbiotic (prebiotic-probiotic) capsule: proprietary BACTILARDII ^® formula, including 9 billion (9x10⁹) CFU* freeze-dried, selected live bacteria cultures and selected live yeast cultures per capsule, acacia fibre, potato starch – carrier, vitamin C (L-ascorbic acid) of natural origin 1.5 mg / capsule – antioxidant, coating ingredient: hydroxypropyl methylcellulose (HPMC). Postbiotic capsule: butyrate granules (as triglyceride) in sunflower oil 380 mg / capsule, expressed as butyric acid 91 mg / capsule, coating ingredients: hydroxypropyl methylcellulose (HPMC), copper complexes of chlorophylls and chlorophyllins – colouring agent.

Ingredient contents in the daily dose of the product

1 capsule

2 capsules

Synbiotic capsule (prebiotic-probiotic)

BACTILARDII^® formula containing:

380 mg

760 mg

bacterial strains

8 x 10⁹ CFU*

1.6 x 10¹⁰ CFU*

Bifidobacterium bifidum Rosell^® R0071

Lactobacillus helveticus Rosell^® R0052

Lactobacillus rhamnosus Rosell^® R0011

Bifidobacterium longum Rosell^® R0175

yeast strains

1 x 10⁹ CFU*

2 x 10⁹ CFU*

Saccharomyces boulardii CNCM I-1079

acacia fibre

Postbiotic capsule

Butyrate (as triglyceride)

114 mg

228 mg

expressed as butyric acid

91 mg

182 mg

The quantity of live micro-organisms is guaranteed until the expiry date of the product, provided that the storage conditions indicated on the label are complied with.

Directions for use: Adults and children over 12 years of age: 1 capsule from each container per day to be washed down with cool water. The combined use involves 2 capsules taken simultaneously – the synbiotic in the first capsule and the postbiotic in the second capsule. If necessary, the use of each capsule may be increased to twice a day. Do not exceed the recommended maximum daily dose. Children aged 7 to 12: the product (both capsules) can be used upon prior consultation with a doctor. Children aged 3 to 7 and pregnant or breast-feeding women: using the synbiotic capsules should be consulted with a doctor. The use of postbiotic capsules is not recommended. The product is not intended for children under 3 years of age.

The capsules are only intended for children who can swallow a capsule. In children who cannot swallow the capsule, the contents of the capsule can be poured out and given on a teaspoon, or additionally dissolved in a small amount of water and taken immediately after preparation.

For antibiotic therapy, it is recommended to use the preparation during the period of taking antibiotic, preferably 1 hour after taking the medicine. It is also recommended to continue to take the supplement for 7-10 days following the end of the antibiotic therapy.

For travels abroad, especially to exotic countries and tropical areas, use the preparation 5 days before departure, for the entire stay, and 5 days after returning from abroad.

The product should not be used as a substitute for a varied diet. Balanced diet and healthy lifestyle are the basis for proper functioning of human body.

Storage: Store at room temperature (20-25°C), out of reach of young children. It does not require refrigeration.

Take care of the environment with DUOLIFE and sort your waste!

After using up the product, think about the environment. Throw the cardboard, labels, containers and leaflet into the appropriate waste bins. You can use the table below.

Environmental table:

Precautions: hypersensitivity to any of the product ingredients. Postbiotic capsules should not be used in children under 7 years of age, pregnant or breastfeeding women. Do not use the product in children under 3 years of age.